The monograph has been dedicated to the analysis of structural and functional changes in the central nervous system of the experimental animals exposed to the isolated and combined effects of space flight factors. There have been shown many changes, which took place in the various anatomic-physiological formations of the brain, and evaluated their significance in organism's responses to the effects of ionizing and nonionizing radiation, hyperoxia, hypoxia, accelerations, vibrations and combined effects of some of those factors. The synergistic, antagonistic and cumulative (simple addition) effects of the investigated stressors along with the radiation factor on the CNS have been stated. This review is prescribed for the specialists in space biology, for physiologists, pathophysiologists, biochemists, radiobiologists and physicians.
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